tsdate is a scalable method for estimating the age of ancestral nodes in a tree sequence. The method uses a coalescent prior and updates node times on the basis of the number of mutations along each edge of the tree sequence (i.e. using the “molecular clock”).

The method is designed to operate on the output of tsinfer, which efficiently infers tree sequence topologies from large genetic datasets. tsdate and tsinfer are scalable to the largest genomic datasets currently available.


This documentation is currently under development. Please wait to use tsdate in your published work until the release of our preprint.